Center for Preclinical Research Excellence

Why CPRE ?

The main goal of Shri Vishnu College of Pharmacy led Center for Preclinical Research Excellence (SVCPs-CPRE) is to train, support and collaborate with pharmacy, life science and multidisciplinary researchers (academia or industry) engaged in unraveling mysteries of physiology, pathophysiology and response to pharmacotherapy or non-pharmacotherapy strategies on live experimental animals, namely mice and rats. All animals in this center are maintained as per norms and the center is committed to the ethical principles of 3Rs (Reduction, Refinement and Replacement). Preclinical screening (studies on animals; Nonclinical) of chemical or  biological agents for safety and efficacy is a prerequisite as per regulatory authorities (eg. ICMR, EMA, FDA etc) to test agents in clinical trials (studies in human beings). Testing of agents in well designed and controlled  preclinical and clinical studies gives valuable information with regard to safety, therapeutic efficacy and effectiveness of agent, thereby allowing regulatory authorities to give approval for medical use in human beings. The center is gearing up to offer preliminary toxicology studies and models mimicking a wide variety of human disorders to facilitate the discovery and development of safe, effective and affordable drugs for betterment of human health. This effort is a part of SVCPs commitment to become a Center of Excellence in pharmaceutical education and research.

Our Center, Your Strength, Your Problem/ Challenge,

Our Challenge/Strength CPRE (Center for Preclinical Research Excellence),  Believes in  CPRE (Collaboration for Preclinical Research Experience)

CPRE: Objectives

  •  To facilitate new drug discovery from natural sources and synthetic molecules
  •  To validate and rationalize Indian system of medicine using modern scientific experimental studies
  •  To provide advanced research skill training to young professionals from academia and industry
  •  To bridge the gap between Academics and Industry research
  •  To develop novel animal models for unmet medical disorders 
  •  To offer expertise and support for in vivo evaluation of formulations, natural products to PG students, research scholars, post doctoral fellows etc 
  •  To establish itself as center of excellence for preclinical research and training

CPRE: Highlights

  •  Unique state-of-the art facility with special focus on preclinical pharmacological  drug  screening 
  •  Led by expert preclinical pharmacologists with decades of research and managerial experience in leading academic and research institutes in India and abroad 
  •  Equipped with video recording systems for different Mazes, stereotaxy, biochemical analysers, ELISA reader, spectrophotometer etc
  •  Supported by in-house/campus experts from 

Center for Analytical Research Excellence (CARE), 

Center for Nanotechnology Research Excellence (CNRE), 

Center for Novel Formulations Excellence (CNFE), 

Center for Nanotechnology Research Excellence (CNRE), 

Center for Imaging and Immunohistochemistry Excellence (CII), 

Center of Excellence – IoT, 

Center of Excellence – Assistive Technologies  etc    

CPRE: Operation Model

  •  Offers wide array of pharmacological models for screening synthetic molecules, biologicals, Indian system of medicines etc on cost-to-cost basis
  •  Potential test article can be enabled for further development with a mutual appropriate undertaking
  •  Guides proper selection of suitable model(s) for screening activity. Provides expert guidance for data analysis, presentation and publication/ patent as per the need on payment basis
  •  Open for collaborative research with academicians or Industry researchers on mutual agreement terms and conditions
  •  Develops new animal models for screening as per the customer needs 
  •  Conducts workshops and trainings on “Experimental Pharmacology techniques – Basic Training” and “Experimental Pharmacology techniques – Advanced Training”
  •  Participate/support in Joint Proposals for grants from national and international authorities 

CPRE: Value Addition to SVCP

  •  Best-in-class facility among Pharmacy colleges in India
  •  A leading centre of traning in Pharmacology among Pharmacy colleges in India
  •  Potential to fulfill the dreams of many biologists in academia*, small and medium size R&D centers
  •  Fully equipped to validate the claims of Indian system of traditional medicine for wide variety of indications
  •  Capable of discovering novel molecules for highly unmet medical disorders 
  •  Facilitates ideation for intra- and inter-college collaborations
  •  Potential for collaboration with National and International organizations